Reduced quinone reductase 2 in complex with CK2 inhibitor DMAT

Summary for 4U7F

Related4U7G 4U7H
DescriptorRibosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywordsreduced quinone reductase 2, dmat, ck2 inhibitor, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P16083
Total number of polymer chains2
Total molecular weight54354.17
Leung, K.K.,Shilton, B.H. (deposition date: 2014-07-30, release date: 2015-02-11, Last modification date: 2017-11-22)
Primary citation
Leung, K.K.,Shilton, B.H.
Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT.
Biochemistry, 54:47-59, 2015
PubMed: 25379648 (PDB entries with the same primary citation)
DOI: 10.1021/bi500959t
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.223600.8%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16