4RG2
Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand
Summary for 4RG2
Entry DOI | 10.2210/pdb4rg2/pdb |
Descriptor | Tumor suppressor p53-binding protein 1, 3-bromo-N-[3-(tert-butylamino)propyl]benzamide, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | 53bp1 tudor, structural genomics, structural genomics consortium, sgc, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q12888 |
Total number of polymer chains | 2 |
Total formula weight | 28743.22 |
Authors | Dong, A.,Mader, P.,James, L.,Perfetti, M.,Tempel, W.,Frye, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Structural Genomics Consortium (SGC) (deposition date: 2014-09-29, release date: 2014-10-15, Last modification date: 2023-09-20) |
Primary citation | Perfetti, M.T.,Baughman, B.M.,Dickson, B.M.,Mu, Y.,Cui, G.,Mader, P.,Dong, A.,Norris, J.L.,Rothbart, S.B.,Strahl, B.D.,Brown, P.J.,Janzen, W.P.,Arrowsmith, C.H.,Mer, G.,McBride, K.M.,James, L.I.,Frye, S.V. Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. ACS Chem. Biol., 10:1072-1081, 2015 Cited by PubMed: 25590533DOI: 10.1021/cb500956g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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