4RG2
Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 3OO A 1701 |
| Chain | Residue |
| A | TRP1495 |
| B | HOH1817 |
| B | HOH1870 |
| A | ASP1521 |
| A | TYR1523 |
| A | MET1584 |
| B | TRP1495 |
| B | TYR1502 |
| B | PHE1519 |
| B | ASP1521 |
| B | MET1584 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1702 |
| Chain | Residue |
| A | ASP1550 |
| A | GLU1551 |
| A | TYR1552 |
| A | PHE1553 |
| A | SER1554 |
| B | ASP1509 |
| B | HOH1835 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1703 |
| Chain | Residue |
| A | LYS1505 |
| A | ARG1508 |
| A | LEU1518 |
| A | HOH1903 |
| A | HOH1910 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1701 |
| Chain | Residue |
| B | GLY1511 |
| B | LYS1514 |
| B | TYR1515 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Region: {"description":"Interaction with dimethylated histone H4","evidences":[{"source":"PubMed","id":"17190600","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
