4RCJ

Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA

Summary for 4RCJ

• Entry DOI: 10.2210/pdb4rcj/pdb
• Related: 4RCI 4RCM
• Descriptor: YTH domain-containing family protein 1, RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q9BYJ9
• Total number of polymer chains: 2
• Total formula weight: 23848.12

Authors

Tempel, W.,Xu, C.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2014-09-16, release date: 2014-11-12, Last modification date: 2023-09-20)

• Primary citation: Xu, C.,Liu, K.,Ahmed, H.,Loppnau, P.,Schapira, M.,Min, J.; Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.; J.Biol.Chem., 290:24902-24913, 2015; PubMed: 26318451; DOI: 10.1074/jbc.M115.680389

Experimental method

X-RAY DIFFRACTION (1.6 Å)