4QMY
MST3 IN COMPLEX WITH STAUROSPORINE
Summary for 4QMY
| Entry DOI | 10.2210/pdb4qmy/pdb |
| Related | 4QML 4QMM 4QMN 4QMO 4QMP 4QMQ 4QMS 4QMT 4QMV 4QMW 4QMX 4QMY 4QMZ |
| Descriptor | SERINE/THREONINE-PROTEIN KINASE 24, STAUROSPORINE, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | protein kinase, mst3, stk24, sterile 20-like kinase, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q9Y6E0 |
| Total number of polymer chains | 1 |
| Total formula weight | 35587.99 |
| Authors | Olesen, S.H.,Watts, C.,Zhu, J.-Y.,Schonbrunn, E. (deposition date: 2014-06-16, release date: 2015-07-01, Last modification date: 2023-09-20) |
| Primary citation | Olesen, S.H.,Zhu, J.Y.,Martin, M.P.,Schonbrunn, E. Discovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3). Chemmedchem, 11:1137-1144, 2016 Cited by PubMed: 27135311DOI: 10.1002/cmdc.201600115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.883 Å) |
Structure validation
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