4QBC
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer
Summary for 4QBC
| Entry DOI | 10.2210/pdb4qbc/pdb |
| Related | 1JQZ 1JY0 1RG8 2AFG 3FJE 3FJF 3FJH 3FJK 4Q91 4Q9G 4Q9P 4QAL |
| Descriptor | Fibroblast growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | beta-trefoil, growth factor, fgfr binding, heparin binding, protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P05230 |
| Total number of polymer chains | 2 |
| Total formula weight | 33649.58 |
| Authors | Blaber, M.,Xia, X. (deposition date: 2014-05-07, release date: 2015-03-11, Last modification date: 2024-02-28) |
| Primary citation | Xia, X.,Longo, L.M.,Blaber, M. Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104:566-576, 2015 Cited by PubMed: 25312595DOI: 10.1002/jps.24188 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.519 Å) |
Structure validation
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