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4Q91

Crystal structure of C16A/K12V/C117V/P134V mutant of human acidic fibroblast growth factor

Summary for 4Q91
Entry DOI10.2210/pdb4q91/pdb
Related1JQZ 1JY0 1RG8 2AFG 3FJE 3FJF 3FJH 3FJK 4Q9G 4Q9P 4QAL
DescriptorFibroblast growth factor 1, FORMIC ACID, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordsbeta-trefoil, growth factor, fgfr binding, heparin binding, extracellular matrix, protein binding
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P05230
Total number of polymer chains2
Total formula weight33570.37
Authors
Xia, X.,Blaber, M. (deposition date: 2014-04-28, release date: 2015-03-11, Last modification date: 2024-02-28)
Primary citationXia, X.,Longo, L.M.,Blaber, M.
Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104:566-576, 2015
Cited by
PubMed: 25312595
DOI: 10.1002/jps.24188
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.799 Å)
Structure validation

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