4QBC

Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fibroblast growth factor 1	polymer	146	16684.7	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	FGF-1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1
2	C (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	D, E, F, G (A, B)	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
4	H, I (A, B)	water	water		18.0	410	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Thr 117	Cys 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33369.4
Non-Polymers*	Number of molecules	5
	Total formula weight	280.2
All*	Total formula weight	33649.6

*Water molecules are not included.