4PJ6
Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site
Summary for 4PJ6
Entry DOI | 10.2210/pdb4pj6/pdb |
Descriptor | Leucyl-cystinyl aminopeptidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total) |
Functional Keywords | aminopeptidase, metalloprotease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 204621.70 |
Authors | Hermans, S.J.,Ascher, D.B.,Hancock, N.C.,Holien, J.K.,Michell, B.,Morton, C.J.,Parker, M.W. (deposition date: 2014-05-12, release date: 2014-12-03, Last modification date: 2023-12-27) |
Primary citation | Hermans, S.J.,Ascher, D.B.,Hancock, N.C.,Holien, J.K.,Michell, B.J.,Yeen Chai, S.,Morton, C.J.,Parker, M.W. Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Sci., 24:190-199, 2015 Cited by PubMed: 25408552DOI: 10.1002/pro.2604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
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