4PDC
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
Summary for 4PDC
Entry DOI | 10.2210/pdb4pdc/pdb |
Related | 1HYR 1JSK 1KCG 1MPU 4FFE |
Descriptor | NKG2-D type II integral membrane protein, CPXV018 protein (3 entities in total) |
Functional Keywords | secreted viral protein, immune evasion, orthopoxvirus, mhc-like fold, nk cell receptor ligand, structural genomics, center for structural genomics of infectious diseases, csgid, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 92772.18 |
Authors | Lazear, E.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-04-17, release date: 2014-05-21, Last modification date: 2023-09-27) |
Primary citation | Lazear, E.,Sun, M.M.,Wang, X.,Geurs, T.L.,Nelson, C.A.,Campbell, J.A.,Lippold, D.,Krupnick, A.S.,Davis, R.S.,Carayannopoulos, L.N.,French, A.R.,Fremont, D.H. Structural basis of cowpox evasion of NKG2D immunosurveillance Biorxiv, 2019 Cited by DOI: 10.1101/796862PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.991 Å) |
Structure validation
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