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4P9Z

Grb2 SH2 complexed with a pTyr-Ac6c-Asn tripeptide

Summary for 4P9Z
Entry DOI10.2210/pdb4p9z/pdb
Related3S8O 4P9V
DescriptorGrowth factor receptor-bound protein 2, NMI-PTR-02K-ASN-NH2, GLYCEROL, ... (6 entities in total)
Functional Keywordsgrb2 sh2, cation-pi interaction, signaling protein-antagonist complex, signaling protein/antagonist
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight14687.85
Authors
Clements, J.H.,Martin, S.F. (deposition date: 2014-04-06, release date: 2014-06-18, Last modification date: 2023-12-27)
Primary citationMyslinski, J.M.,Clements, J.H.,Martin, S.F.
Protein-ligand interactions: Probing the energetics of a putative cation-pi interaction.
Bioorg.Med.Chem.Lett., 24:3164-3167, 2014
Cited by
PubMed: 24856058
DOI: 10.1016/j.bmcl.2014.04.114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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