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4P9Z

Grb2 SH2 complexed with a pTyr-Ac6c-Asn tripeptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Growth factor receptor-bound protein 2polymer11713758.51UniProt (P62993)
Pfam (PF00017)
Homo sapiens (Human)Adapter protein GRB2,Protein Ash,SH2/SH3 adapter GRB2
2B
(B)
NMI-PTR-02K-ASN-NH2polymer5683.71synthetic construct
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D, E
(A)
ACETATE IONnon-polymer59.02Chemie (ACT)
5F
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6G, H
(A, B)
waterwater18.066Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14442.2
Non-Polymers*Number of molecules4
Total formula weight245.6
All*Total formula weight14687.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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