4P5D
CRYSTAL STRUCTURE OF RAT DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE
Summary for 4P5D
Entry DOI | 10.2210/pdb4p5d/pdb |
Related | 4FYI |
Descriptor | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 6-(naphthalen-2-yl)-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine, SULFATE ION, ... (4 entities in total) |
Functional Keywords | n-glycosidase, inhibitor, hydrolase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Cytoplasm (By similarity): O35820 |
Total number of polymer chains | 2 |
Total formula weight | 35359.45 |
Authors | Padilla, A.,Labesse, G.,Kaminski, P.A. (deposition date: 2014-03-16, release date: 2014-08-20, Last modification date: 2023-12-20) |
Primary citation | Amiable, C.,Paoletti, J.,Haouz, A.,Padilla, A.,Labesse, G.,Kaminski, P.A.,Pochet, S. 6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities. Eur.J.Med.Chem., 85C:418-437, 2014 Cited by PubMed: 25108359DOI: 10.1016/j.ejmech.2014.07.110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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