4P5D
CRYSTAL STRUCTURE OF RAT DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| A | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
| C | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| C | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue N6P C 201 |
| Chain | Residue |
| C | TYR13 |
| C | ALA58 |
| C | ILE65 |
| C | ASN69 |
| C | SER87 |
| C | GLY89 |
| C | GLU93 |
| C | SER117 |
| C | MET119 |
| C | HOH304 |
| C | HOH306 |
| C | CYS15 |
| C | HOH330 |
| C | HOH344 |
| C | GLY16 |
| C | SER17 |
| C | ILE18 |
| C | ARG19 |
| C | GLY20 |
| C | HIS45 |
| C | GLU57 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue N6P A 201 |
| Chain | Residue |
| A | TYR13 |
| A | CYS15 |
| A | GLY16 |
| A | SER17 |
| A | ILE18 |
| A | ARG19 |
| A | GLY20 |
| A | HIS45 |
| A | VAL46 |
| A | GLU57 |
| A | ALA58 |
| A | ILE65 |
| A | ASN69 |
| A | SER87 |
| A | GLY89 |
| A | VAL90 |
| A | GLU93 |
| A | SER117 |
| A | MET119 |
| A | HOH305 |
| A | HOH315 |
| A | HOH369 |
| A | HOH385 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | ARG34 |
| A | ARG36 |
| A | ARG37 |
| A | HOH304 |
| A | HOH317 |
| A | HOH382 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O43598","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
