4OV5
Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket
Summary for 4OV5
Entry DOI | 10.2210/pdb4ov5/pdb |
Related | 1AQD |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, HLA class I histocompatibility antigen, A-2 alpha chain, ... (4 entities in total) |
Functional Keywords | ig-like domain, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 Membrane; Single-pass type I membrane protein: P01892 |
Total number of polymer chains | 18 |
Total formula weight | 269192.27 |
Authors | Trenh, P.,Yin, L.,Stern, L.J. (deposition date: 2014-02-20, release date: 2014-07-16, Last modification date: 2023-09-20) |
Primary citation | Yin, L.,Trenh, P.,Guce, A.,Wieczorek, M.,Lange, S.,Sticht, J.,Jiang, W.,Bylsma, M.,Mellins, E.D.,Freund, C.,Stern, L.J. Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289:23449-23464, 2014 Cited by PubMed: 25002586DOI: 10.1074/jbc.M114.585539 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.199 Å) |
Structure validation
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