4OV5
Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006955 | biological_process | immune response |
A | 0016020 | cellular_component | membrane |
A | 0019882 | biological_process | antigen processing and presentation |
A | 0042613 | cellular_component | MHC class II protein complex |
B | 0006955 | biological_process | immune response |
B | 0016020 | cellular_component | membrane |
B | 0019882 | biological_process | antigen processing and presentation |
B | 0042613 | cellular_component | MHC class II protein complex |
D | 0006955 | biological_process | immune response |
D | 0016020 | cellular_component | membrane |
D | 0019882 | biological_process | antigen processing and presentation |
D | 0042613 | cellular_component | MHC class II protein complex |
E | 0006955 | biological_process | immune response |
E | 0016020 | cellular_component | membrane |
E | 0019882 | biological_process | antigen processing and presentation |
E | 0042613 | cellular_component | MHC class II protein complex |
G | 0006955 | biological_process | immune response |
G | 0016020 | cellular_component | membrane |
G | 0019882 | biological_process | antigen processing and presentation |
G | 0042613 | cellular_component | MHC class II protein complex |
H | 0006955 | biological_process | immune response |
H | 0016020 | cellular_component | membrane |
H | 0019882 | biological_process | antigen processing and presentation |
H | 0042613 | cellular_component | MHC class II protein complex |
J | 0006955 | biological_process | immune response |
J | 0016020 | cellular_component | membrane |
J | 0019882 | biological_process | antigen processing and presentation |
J | 0042613 | cellular_component | MHC class II protein complex |
K | 0006955 | biological_process | immune response |
K | 0016020 | cellular_component | membrane |
K | 0019882 | biological_process | antigen processing and presentation |
K | 0042613 | cellular_component | MHC class II protein complex |
M | 0006955 | biological_process | immune response |
M | 0016020 | cellular_component | membrane |
M | 0019882 | biological_process | antigen processing and presentation |
M | 0042613 | cellular_component | MHC class II protein complex |
N | 0006955 | biological_process | immune response |
N | 0016020 | cellular_component | membrane |
N | 0019882 | biological_process | antigen processing and presentation |
N | 0042613 | cellular_component | MHC class II protein complex |
P | 0006955 | biological_process | immune response |
P | 0016020 | cellular_component | membrane |
P | 0019882 | biological_process | antigen processing and presentation |
P | 0042613 | cellular_component | MHC class II protein complex |
Q | 0006955 | biological_process | immune response |
Q | 0016020 | cellular_component | membrane |
Q | 0019882 | biological_process | antigen processing and presentation |
Q | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH |
Chain | Residue | Details |
B | TYR171-HIS177 | |
A | TYR161-HIS167 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:21543847 |
Chain | Residue | Details |
C | TYR14 | |
H | TRP61 | |
H | HIS81 | |
H | ASN82 | |
K | ASP57 | |
K | TRP61 | |
K | HIS81 | |
K | ASN82 | |
N | ASP57 | |
N | TRP61 | |
N | HIS81 | |
F | TYR14 | |
N | ASN82 | |
Q | ASP57 | |
Q | TRP61 | |
Q | HIS81 | |
Q | ASN82 | |
I | TYR14 | |
L | TYR14 | |
O | TYR14 | |
R | TYR14 | |
E | HIS81 | |
E | ASN82 | |
H | ASP57 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:8145819 |
Chain | Residue | Details |
B | ARG93 | |
M | ALA52 | |
P | GLY49 | |
P | ALA52 | |
E | ARG93 | |
H | ARG93 | |
K | ARG93 | |
N | ARG93 | |
Q | ARG93 | |
J | GLY49 | |
J | ALA52 | |
M | GLY49 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19303388, ECO:0000269|PubMed:24190431 |
Chain | Residue | Details |
B | ASN19 | |
E | ASN19 | |
H | ASN19 | |
K | ASN19 | |
N | ASN19 | |
Q | ASN19 |
site_id | SWS_FT_FI4 |
Number of Residues | 6 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
Chain | Residue | Details |
A | SER53 | |
D | SER53 | |
G | SER53 | |
J | SER53 | |
M | SER53 | |
P | SER53 |
site_id | SWS_FT_FI5 |
Number of Residues | 6 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | GLU55 | |
D | GLU55 | |
G | GLU55 | |
J | GLU55 | |
M | GLU55 | |
P | GLU55 |
site_id | SWS_FT_FI6 |
Number of Residues | 6 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN62 | |
D | ASN62 | |
G | ASN62 | |
J | ASN62 | |
M | ASN62 | |
P | ASN62 |
site_id | SWS_FT_FI7 |
Number of Residues | 6 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN69 | |
D | ASN69 | |
G | ASN69 | |
J | ASN69 | |
M | ASN69 | |
P | ASN69 |
site_id | SWS_FT_FI8 |
Number of Residues | 6 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ARG76 | |
D | ARG76 | |
G | ARG76 | |
J | ARG76 | |
M | ARG76 | |
P | ARG76 |
site_id | SWS_FT_FI9 |
Number of Residues | 12 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
Chain | Residue | Details |
A | ASN78 | |
M | ASN118 | |
P | ASN78 | |
P | ASN118 | |
A | ASN118 | |
D | ASN78 | |
D | ASN118 | |
G | ASN78 | |
G | ASN118 | |
J | ASN78 | |
J | ASN118 | |
M | ASN78 |