4OV5
Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, D, G, J, M...) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 182 | 21155.9 | 6 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | HLA-DR1, MHC class II antigen DRA |
| 2 | B, D, F, H, J... (B, E, H, K, N...) | HLA class II histocompatibility antigen, DRB1-1 beta chain | polymer | 190 | 22080.7 | 6 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | HLA-DR1, MHC class II antigen DRB1*1, DR-1, DR1 |
| 3 | M, N, O, P, Q... (C, F, I, L, O...) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 14 | 1628.8 | 6 | UniProt (P01892) UniProt (by SIFTS) (P04439) | Homo sapiens | HLA-A2, MHC class I antigen A*2 |
| 4 | AA, BA, CA, DA, EA... (M, N, P, Q, C...) | water | water | 18.0 | 639 | Chemie (HOH) |
Sequence modifications
C, F, I, L, O, R: 2 - 15 (UniProt: P01892)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | Trp 131 | engineered mutation |
| Leu 13 | Gln 139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 269192.3 | |
| All* | Total formula weight | 269192.3 |
