4ONF
Fab fragment of 3D6 in complex with amyloid beta 1-7
Summary for 4ONF
Entry DOI | 10.2210/pdb4onf/pdb |
Related | 4ONG |
Descriptor | 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ... (4 entities in total) |
Functional Keywords | antibody, amyloid beta peptide, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 3 |
Total formula weight | 48981.60 |
Authors | Feinberg, H.,Saldanha, J.W.,Diep, L.,Goel, A.,Widom, A.,Veldman, G.M.,Weis, W.I.,Schenk, D.,Basi, G.S. (deposition date: 2014-01-28, release date: 2014-06-11, Last modification date: 2023-09-20) |
Primary citation | Feinberg, H.,Saldanha, J.W.,Diep, L.,Goel, A.,Widom, A.,Veldman, G.M.,Weis, W.I.,Schenk, D.,Basi, G.S. Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab. Alzheimers Res Ther, 6:31-31, 2014 Cited by PubMed: 25024748DOI: 10.1186/alzrt261 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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