4ONF

Fab fragment of 3D6 in complex with amyloid beta 1-7

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN

Chain	Residue
H	GLY33
H	SER106
H	HOH482
L	ASP31
L	TYR37
L	TRP94
L	GLY96
L	THR97
L	ARG101
P	HOH101
P	HOH102
H	MET34
P	HOH103
P	HOH104
P	HOH106
P	HOH107
H	TRP47
H	SER50
H	ILE51
H	ARG52
H	TYR59
H	TYR99
H	SER105

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR197-HIS203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:11274207, ECO:0000269|PubMed:26898943

Chain	Residue	Details
P	HIS6

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Cleavage; by caspase-6; when associated with variant 670-N-L-671

Chain	Residue	Details
P	ASP1

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by ACE => ECO:0000269|PubMed:11604391, ECO:0000269|PubMed:16154999

Chain	Residue	Details
P	ASP7

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