4NM8

Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin

Summary for 4NM8

• Entry DOI: 10.2210/pdb4nm8/pdb
• Related: 4NM4
• EMDB information: 5793 5794
• Descriptor: Hemagglutinin HA1 Chain, Hemagglutinin HA2 Chain, Antibody CR8043, Light Chain, ... (6 entities in total)
• Functional Keywords: viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, immunoglobulin', viral protein/immune system
• Biological source: Influenza A virus (strain A/Hong Kong/1/1968 H3N2); More
• Total number of polymer chains: 12
• Total formula weight: 318376.41

Authors

Lee, P.S.,Wilson, I.A. (deposition date: 2013-11-14, release date: 2013-12-25, Last modification date: 2023-09-20)

• Primary citation: Friesen, R.H.,Lee, P.S.,Stoop, E.J.,Hoffman, R.M.,Ekiert, D.C.,Bhabha, G.,Yu, W.,Juraszek, J.,Koudstaal, W.,Jongeneelen, M.,Korse, H.J.,Ophorst, C.,Brinkman-van der Linden, E.C.,Throsby, M.,Kwakkenbos, M.J.,Bakker, A.Q.,Beaumont, T.,Spits, H.,Kwaks, T.,Vogels, R.,Ward, A.B.,Goudsmit, J.,Wilson, I.A.; A common solution to group 2 influenza virus neutralization.; Proc.Natl.Acad.Sci.USA, 111:445-450, 2014; PubMed: 24335589; DOI: 10.1073/pnas.1319058110

Experimental method

X-RAY DIFFRACTION (4.0041 Å)