4NM8

Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0046789	molecular_function	host cell surface receptor binding
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0046789	molecular_function	host cell surface receptor binding
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0046789	molecular_function	host cell surface receptor binding
D	0019031	cellular_component	viral envelope
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0046789	molecular_function	host cell surface receptor binding
E	0019031	cellular_component	viral envelope
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0046789	molecular_function	host cell surface receptor binding
F	0019031	cellular_component	viral envelope
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0046789	molecular_function	host cell surface receptor binding
L	0002250	biological_process	adaptive immune response
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0050853	biological_process	B cell receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0071738	cellular_component	IgD immunoglobulin complex
L	0071742	cellular_component	IgE immunoglobulin complex
L	0071745	cellular_component	IgA immunoglobulin complex
L	0071753	cellular_component	IgM immunoglobulin complex
L	0072562	cellular_component	blood microparticle
M	0002250	biological_process	adaptive immune response
M	0003823	molecular_function	antigen binding
M	0005576	cellular_component	extracellular region
M	0005615	cellular_component	extracellular space
M	0005886	cellular_component	plasma membrane
M	0006955	biological_process	immune response
M	0016064	biological_process	immunoglobulin mediated immune response
M	0019814	cellular_component	immunoglobulin complex
M	0050853	biological_process	B cell receptor signaling pathway
M	0070062	cellular_component	extracellular exosome
M	0071735	cellular_component	IgG immunoglobulin complex
M	0071738	cellular_component	IgD immunoglobulin complex
M	0071742	cellular_component	IgE immunoglobulin complex
M	0071745	cellular_component	IgA immunoglobulin complex
M	0071753	cellular_component	IgM immunoglobulin complex
M	0072562	cellular_component	blood microparticle
N	0002250	biological_process	adaptive immune response
N	0003823	molecular_function	antigen binding
N	0005576	cellular_component	extracellular region
N	0005615	cellular_component	extracellular space
N	0005886	cellular_component	plasma membrane
N	0006955	biological_process	immune response
N	0016064	biological_process	immunoglobulin mediated immune response
N	0019814	cellular_component	immunoglobulin complex
N	0050853	biological_process	B cell receptor signaling pathway
N	0070062	cellular_component	extracellular exosome
N	0071735	cellular_component	IgG immunoglobulin complex
N	0071738	cellular_component	IgD immunoglobulin complex
N	0071742	cellular_component	IgE immunoglobulin complex
N	0071745	cellular_component	IgA immunoglobulin complex
N	0071753	cellular_component	IgM immunoglobulin complex
N	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
B	ASN154
D	ASN154
F	ASN154

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site_id	SWS_FT_FI2
Number of Residues	15
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	ASN22
C	ASN285
E	ASN22
E	ASN38
E	ASN81
E	ASN165
E	ASN285
A	ASN38
A	ASN81
A	ASN165
A	ASN285
C	ASN22
C	ASN38
C	ASN81
C	ASN165

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