4MUV

M. loti cyclic-nucleotide binding domain mutant displaying inverted ligand selectivity, cyclic-GMP bound

Summary for 4MUV

Entry DOI	10.2210/pdb4muv/pdb
Related	1U12 1VP6 3BEH 3CL1 3CLP 3CO2
Descriptor	Cyclic nucleotide-gated potassium channel mll3241, CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, ... (4 entities in total)
Functional Keywords	mlotik1 cnbd mutant, cgmp-complex, cyclic-nucleotide binding, membrane protein domain, metal transport, nucleotide binding protein
Biological source	Mesorhizobium loti
Cellular location	Cell membrane; Multi-pass membrane protein: Q98GN8
Total number of polymer chains	2
Total formula weight	30738.69
Authors	Fonseca, F.,Pessoa, J.,Morais-Cabral, J.H. (deposition date: 2013-09-23, release date: 2014-06-25, Last modification date: 2023-09-20)
Primary citation	Pessoa, J.,Fonseca, F.,Furini, S.,Morais-Cabral, J.H. Determinants of ligand selectivity in a cyclic nucleotide-regulated potassium channel. J.Gen.Physiol., 144:41-54, 2014 Cited by PubMed: 24981229 DOI: 10.1085/jgp.201311145 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation