4MUV
M. loti cyclic-nucleotide binding domain mutant displaying inverted ligand selectivity, cyclic-GMP bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic nucleotide-gated potassium channel mll3241 | polymer | 142 | 15001.2 | 2 | UniProt (Q98GN8) Pfam (PF00027) | Mesorhizobium loti | MlotiK1 channel |
| 2 | C, E (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) | |||
| 3 | D, F (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A, B: 216 - 355 (UniProt: Q98GN8)
| PDB | External Database | Details |
|---|---|---|
| Gly 214 | - | expression tag |
| Ser 215 | - | expression tag |
| Ser 284 | Thr 284 | engineered mutation |
| Ser 288 | Val 288 | engineered mutation |
| Asp 352 | Ala 352 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30002.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 736.4 | |
| All* | Total formula weight | 30738.7 |
