4MUV
M. loti cyclic-nucleotide binding domain mutant displaying inverted ligand selectivity, cyclic-GMP bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic nucleotide-gated potassium channel mll3241 | polymer | 142 | 15001.2 | 2 | UniProt (Q98GN8) | Mesorhizobium loti | MlotiK1 channel |
| 2 | C, E (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 3 | D, F (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A, B: 216 - 355 (UniProt: Q98GN8)
| PDB | External Database | Details |
|---|---|---|
| Gly 214 | - | expression tag |
| Ser 215 | - | expression tag |
| Ser 284 | Thr 284 | engineered mutation |
| Ser 288 | Val 288 | engineered mutation |
| Asp 352 | Ala 352 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30002.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 736.4 | |
| All* | Total formula weight | 30738.7 |
