4MRF
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Summary for 4MRF
| Entry DOI | 10.2210/pdb4mrf/pdb |
| Related | 4MRD 4MRE 4MRG 4MRH 4NP2 4NP3 |
| Descriptor | CD44 antigen, DIMETHYL SULFOXIDE, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | link module, cell receptor, hyaluronan binding, cell surface, cell adhesion-inhibitor complex, cell adhesion/inhibitor |
| Biological source | Mus musculus (mouse) |
| Cellular location | Cell membrane ; Single-pass type I membrane protein : P15379 |
| Total number of polymer chains | 1 |
| Total formula weight | 17124.08 |
| Authors | Liu, L.K.,Finzel, B. (deposition date: 2013-09-17, release date: 2014-04-16, Last modification date: 2023-09-20) |
| Primary citation | Liu, L.K.,Finzel, B.C. Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors. J.Med.Chem., 57:2714-2725, 2014 Cited by PubMed: 24606063DOI: 10.1021/jm5000276 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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