4MRD
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Summary for 4MRD
Entry DOI | 10.2210/pdb4mrd/pdb |
Related | 4MRE 4MRF 4MRG 4MRH 4NP2 4NP3 |
Descriptor | CD44 antigen, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total) |
Functional Keywords | link module, cell receptor, hyaluronan binding, cell surface, cell adhesion |
Biological source | Mus musculus (mouse) |
Cellular location | Cell membrane ; Single-pass type I membrane protein : P15379 |
Total number of polymer chains | 1 |
Total formula weight | 17483.21 |
Authors | Liu, L.K.,Finzel, B. (deposition date: 2013-09-17, release date: 2014-04-16, Last modification date: 2020-07-29) |
Primary citation | Liu, L.K.,Finzel, B.C. Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors. J.Med.Chem., 57:2714-2725, 2014 Cited by PubMed: 24606063DOI: 10.1021/jm5000276 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
Download full validation report