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4M9F

Dengue virus NS2B-NS3 protease A125C variant at pH 8.5

Summary for 4M9F
Entry DOI10.2210/pdb4m9f/pdb
Related2fom 3U1I 3U1J 4M9I 4M9K 4M9M 4M9T
DescriptorNS2B-NS3 protease (2 entities in total)
Functional Keywordsserine protease, allosteric inhibition, dengue virus protease, trypsin-like protease, conformational flexibility, viral protein
Biological sourceDengue virus 2
More
Cellular locationVirion membrane ; Multi-pass membrane protein : Q91H74
Total number of polymer chains1
Total formula weight26360.48
Authors
Yildiz, M.,Ghosh, S.,Bell, J.A.,Sherman, W.,Hardy, J.A. (deposition date: 2013-08-14, release date: 2013-11-27, Last modification date: 2023-09-20)
Primary citationYildiz, M.,Ghosh, S.,Bell, J.A.,Sherman, W.,Hardy, J.A.
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus.
Acs Chem.Biol., 8:2744-2752, 2013
Cited by
PubMed: 24164286
DOI: 10.1021/cb400612h
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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