4M81

The structure of E292S glycosynthase variant of exo-1,3-beta-glucanase from Candida albicans complexed with 1-fluoro-alpha-D-glucopyranoside (donor) and p-nitrophenyl beta-D-glucopyranoside (acceptor) at 1.86A resolution

Summary for 4M81

Entry DOI	10.2210/pdb4m81/pdb
Related	1CZ1 4M80 4M82
Descriptor	EXO-1,3-BETA-GLUCANASE, alpha-D-glucopyranosyl fluoride, 4-nitrophenyl beta-D-glucopyranoside, ... (5 entities in total)
Functional Keywords	tim barrel, glycoside hydrolase family 5, glycoside hydrolase, cell wall hydrolase, glycosynthase, hydrolase, protein-carbohydrate interaction
Biological source	Candida albicans (yeast)
Total number of polymer chains	1
Total formula weight	46268.80
Authors	Nakatani, Y.,Cutfield, S.M.,Larsen, D.S.,Cutfield, J.F. (deposition date: 2013-08-12, release date: 2014-06-25, Last modification date: 2023-09-20)
Primary citation	Nakatani, Y.,Larsen, D.S.,Cutfield, S.M.,Cutfield, J.F. Major Change in Regiospecificity for the Exo-1,3-beta-glucanase from Candida albicans following Its Conversion to a Glycosynthase. Biochemistry, 53:3318-3326, 2014 Cited by PubMed: 24804868 DOI: 10.1021/bi500239m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation