4LL4

The structure of the TRX and TXNIP complex

Summary for 4LL4

• Entry DOI: 10.2210/pdb4ll4/pdb
• Related: 4GFX 4LL1
• Descriptor: Thioredoxin-interacting protein, Thioredoxin (3 entities in total)
• Functional Keywords: arrestin-like domain, antitumor protein-protein binding complex, antitumor protein/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): Q9H3M7; Nucleus: P10599
• Total number of polymer chains: 4
• Total formula weight: 93511.82

Authors

Hwang, J.,Kim, M.H. (deposition date: 2013-07-09, release date: 2014-02-05, Last modification date: 2023-11-08)

• Primary citation: Hwang, J.,Suh, H.W.,Jeon, Y.H.,Hwang, E.,Nguyen, L.T.,Yeom, J.,Lee, S.G.,Lee, C.,Kim, K.J.,Kang, B.S.,Jeong, J.O.,Oh, T.K.,Choi, I.,Lee, J.O.,Kim, M.H.; The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein; Nat Commun, 5:2958-2958, 2014; PubMed: 24389582; DOI: 10.1038/ncomms3958

Experimental method

X-RAY DIFFRACTION (2.7 Å)