4KTR

Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with isofagomine and glycerol

Summary for 4KTR

• Entry DOI: 10.2210/pdb4ktr/pdb
• Related: 4KTP
• Descriptor: Glycoside hydrolase family 65 central catalytic, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... (12 entities in total)
• Functional Keywords: (alpha/alpha)6 barrel, phosphorylase, transferase
• Biological source: Bacillus selenitireducens
• Total number of polymer chains: 8
• Total formula weight: 708730.88

Authors

Touhara, K.K.,Nihira, T.,Kitaoka, M.,Nakai, H.,Fushinobu, S. (deposition date: 2013-05-21, release date: 2014-05-21, Last modification date: 2024-03-20)

• Primary citation: Touhara, K.K.,Nihira, T.,Kitaoka, M.,Nakai, H.,Fushinobu, S.; Structural basis for reversible phosphorolysis and hydrolysis reactions of 2-O-alpha-glucosylglycerol phosphorylase; J.Biol.Chem., 289:18067-18075, 2014; PubMed: 24828502; DOI: 10.1074/jbc.M114.573212

Experimental method

X-RAY DIFFRACTION (2.3 Å)