4KTR
Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with isofagomine and glycerol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glycoside hydrolase family 65 central catalytic | polymer | 769 | 87435.5 | 8 | UniProt (D6XZ22) Pfam (PF03636) Pfam (PF03632) Pfam (PF03633) | Bacillus selenitireducens | 2-O-alpha-glucosylglycerol phosphorylase |
| 2 | CB, I, KB, OA, QB... (E, A, F, D, G...) | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | non-polymer | 147.2 | 6 | Chemie (IFM) | |||
| 3 | DB, EA, J (E, C, A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 3 | Chemie (1PE) | |||
| 4 | AA, AC, BA, BC, CA... (B, H, C, E, A...) | GLYCEROL | non-polymer | 92.1 | 44 | Chemie (GOL) | |||
| 5 | EB, N (E, A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) | |||
| 6 | KA, PB, T, UB (C, F, A, G) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 7 | AB, BB, DA, JB, NA... (D, B, E, C, A...) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 8 | MB, QA, V, YB (F, D, B, H) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 4 | Chemie (PG4) | |||
| 9 | VA, W (D, B) | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL | non-polymer | 310.4 | 2 | Chemie (7PE) | |||
| 10 | IA (C) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 11 | DC (H) | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL | non-polymer | 398.5 | 1 | Chemie (PE5) | |||
| 12 | EC, FC, GC, HC, IC... (A, B, C, D, E...) | water | water | 18.0 | 1966 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 761 (UniProt: D6XZ22)
| PDB | External Database | Details |
|---|---|---|
| Gln 475 | Glu 475 | engineered mutation |
| Leu 762 | - | expression tag |
| Glu 763 | - | expression tag |
| His 764 | - | expression tag |
| His 765 | - | expression tag |
| His 766 | - | expression tag |
| His 767 | - | expression tag |
| His 768 | - | expression tag |
| His 769 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 699484.4 | |
| Non-Polymers* | Number of molecules | 74 |
| Total formula weight | 9246.5 | |
| All* | Total formula weight | 708730.9 |
