4KKH
The crystal structure of inhibitor-bound JNK3
Summary for 4KKH
Entry DOI | 10.2210/pdb4kkh/pdb |
Related | 4KKE 4KKG |
Descriptor | Mitogen-activated protein kinase 10, cyclopropyl[(3R)-3-({4-[6-hydroxy-2-(naphthalen-2-yl)-1H-benzimidazol-1-yl]pyrimidin-2-yl}amino)piperidin-1-yl]methanone (3 entities in total) |
Functional Keywords | kinase domain, kinase, c-jun, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P53779 |
Total number of polymer chains | 1 |
Total formula weight | 42621.31 |
Authors | Han, B.G.,Shim, M.B.,Ahn, H.C. (deposition date: 2013-05-06, release date: 2014-05-21, Last modification date: 2024-02-28) |
Primary citation | Han, B.G.,Shim, M.B.,Ahn, H.C. The crystal structure of AMP, apo, and inhibitor-bound JNK3 To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report