4KGC
Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM
Summary for 4KGC
Entry DOI | 10.2210/pdb4kgc/pdb |
Descriptor | Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total) |
Functional Keywords | dna-protein complex, nucleosome, ruthenium agents, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (clawed frog,common platanna,platanna) More |
Cellular location | Nucleus: P84233 P62799 P02281 Chromosome . Nucleus : Q6AZJ8 |
Total number of polymer chains | 10 |
Total formula weight | 200792.86 |
Authors | Adhireksan, Z.,Davey, C.A. (deposition date: 2013-04-29, release date: 2014-03-26, Last modification date: 2024-03-20) |
Primary citation | Adhireksan, Z.,Davey, G.E.,Campomanes, P.,Groessl, M.,Clavel, C.M.,Yu, H.,Nazarov, A.A.,Yeo, C.H.,Ang, W.H.,Droge, P.,Rothlisberger, U.,Dyson, P.J.,Davey, C.A. Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity Nat Commun, 5:3462-3462, 2014 Cited by PubMed: 24637564DOI: 10.1038/ncomms4462 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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