4K81

Crystal structure of the Grb14 RA and PH domains in complex with GTP-loaded H-Ras

Summary for 4K81

• Entry DOI: 10.2210/pdb4k81/pdb
• Descriptor: Growth factor receptor-bound protein 14, GTPase HRas, GLYCEROL, ... (6 entities in total)
• Functional Keywords: adaptor protein, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q14449; Cell membrane. Isoform 2: Nucleus: P01112
• Total number of polymer chains: 8
• Total formula weight: 200286.27

Authors

Qamra, R.,Hubbard, S.R. (deposition date: 2013-04-17, release date: 2013-09-04, Last modification date: 2023-09-20)

• Primary citation: Qamra, R.,Hubbard, S.R.; Structural basis for the interaction of the adaptor protein grb14 with activated ras.; Plos One, 8:e72473-e72473, 2013; PubMed: 23967305; DOI: 10.1371/journal.pone.0072473

Experimental method

X-RAY DIFFRACTION (2.4 Å)