4IMO
Crystal structure of wild type human Lipocalin PGDS in complex with substrate analog U44069
Summary for 4IMO
Entry DOI | 10.2210/pdb4imo/pdb |
Related | 4IMN |
Descriptor | Lipocalin-type prostaglandin-D synthase, (5E)-7-{(1R,4S,5S,6R)-5-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl}hept-5-enoic acid, THIOCYANATE ION, ... (4 entities in total) |
Functional Keywords | beta barrel, isomerase, endoplasmic reticulum |
Biological source | Homo sapiens (human) |
Cellular location | Rough endoplasmic reticulum: P41222 |
Total number of polymer chains | 1 |
Total formula weight | 20565.29 |
Authors | Lim, S.M.,Chen, D.,Teo, H.,Roos, A.,Nyman, T.,Tresaugues, L.,Pervushin, K.,Nordlund, P. (deposition date: 2013-01-03, release date: 2013-03-20, Last modification date: 2023-09-20) |
Primary citation | Lim, S.M.,Chen, D.,Teo, H.,Roos, A.,Jansson, A.E.,Nyman, T.,Tresaugues, L.,Pervushin, K.,Nordlund, P. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54:1630-1643, 2013 Cited by PubMed: 23526831DOI: 10.1194/jlr.M035410 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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