4HY6
Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
Summary for 4HY6
Entry DOI | 10.2210/pdb4hy6/pdb |
Descriptor | Heat shock protein HSP 90-alpha, 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one (3 entities in total) |
Functional Keywords | atp binding, molecularchaperone, inhibitor, rossmann fold, molecular chaperone, atp hydrolysis, chaperone-chaperone inhibitor complex, chaperone/chaperone inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P07900 |
Total number of polymer chains | 1 |
Total formula weight | 25888.97 |
Authors | |
Primary citation | Yang, M.,Li, J.,He, J.H. Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1 to be published, |
Experimental method | X-RAY DIFFRACTION (1.649 Å) |
Structure validation
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