4HHQ
Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations
Summary for 4HHQ
Entry DOI | 10.2210/pdb4hhq/pdb |
Related | 1V04 3SRE 3SRG 4HHO |
Descriptor | SERUM PARAOXONASE BY DIRECTED EVOLUTION, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... (5 entities in total) |
Functional Keywords | 6-blades -propeller fold, hydrolase |
Biological source | synthetic construct (artificial gene) |
Total number of polymer chains | 1 |
Total formula weight | 40414.40 |
Authors | Moshe, B.-D.,Grzegorz, W.,Mikael, E.,Israel, S.,Joel, L.S.,Dan, S.T. (deposition date: 2012-10-10, release date: 2013-03-27, Last modification date: 2018-01-24) |
Primary citation | Ben-David, M.,Wieczorek, G.,Elias, M.,Silman, I.,Sussman, J.L.,Tawfik, D.S. Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme. J.Mol.Biol., 425:1028-1038, 2013 Cited by PubMed: 23318950DOI: 10.1016/j.jmb.2013.01.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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