3SRG
Serum paraoxonase-1 by directed evolution at pH 6.5 in complex with 2-hydroxyquinoline
Summary for 3SRG
Entry DOI | 10.2210/pdb3srg/pdb |
Related | 1V04 3SRE |
Descriptor | serum paraoxonase, CALCIUM ION, QUINOLIN-2(1H)-ONE, ... (7 entities in total) |
Functional Keywords | directed evolution, 6-blades-propeller fold, hydrolase |
Biological source | artificial gene |
Total number of polymer chains | 1 |
Total formula weight | 40530.77 |
Authors | Ben David, M.,Elias, M.,Silman, I.,Sussman, J.L.,Tawfik, D.S. (deposition date: 2011-07-07, release date: 2012-03-21, Last modification date: 2023-09-13) |
Primary citation | Ben-David, M.,Elias, M.,Filippi, J.J.,Dunach, E.,Silman, I.,Sussman, J.L.,Tawfik, D.S. Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1. J.Mol.Biol., 418:181-196, 2012 Cited by PubMed: 22387469DOI: 10.1016/j.jmb.2012.02.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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