4GWT

Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid

Summary for 4GWT

Entry DOI	10.2210/pdb4gwt/pdb
Related	2IDH 2KCF 4GWV
Descriptor	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, (2S)-2-hydroxybutanedioic acid (3 entities in total)
Functional Keywords	racemic crystallization, ww domain, proline phosphoser/thr binding, protein binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q13526
Total number of polymer chains	1
Total formula weight	4308.73
Authors	Mortenson, D.E.,Yun, H.G.,Gellman, S.H.,Forest, K.T. (deposition date: 2012-09-03, release date: 2013-10-16, Last modification date: 2023-09-13)
Primary citation	Mortenson, D.E.,Kreitler, D.F.,Yun, H.G.,Gellman, S.H.,Forest, K.T. Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallogr.,Sect.D, 69:2506-2512, 2013 Cited by PubMed: 24311591 DOI: 10.1107/S090744491302444X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation