4GJG

Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.

Summary for 4GJG

Entry DOI	10.2210/pdb4gjg/pdb
Related	1AP4 1J1D 1MXL 1SPY 3SD6 3SWB 4GJE 4GJF
Descriptor	Troponin C, slow skeletal and cardiac muscles, CADMIUM ION, CALCIUM ION, ... (6 entities in total)
Functional Keywords	helix-loop-helix ef-hand motif, contractile protein, calcium sensor, cadmium binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	11214.60
Authors	Zhang, X.,Paetzel, M. (deposition date: 2012-08-09, release date: 2013-02-06, Last modification date: 2024-02-28)
Primary citation	Zhang, X.L.,Tibbits, G.F.,Paetzel, M. The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D, 69:722-734, 2013 Cited by PubMed: 23633581 DOI: 10.1107/S0907444913001182 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation