4GIV

Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ183

Summary for 4GIV

• Entry DOI: 10.2210/pdb4giv/pdb
• Related: 2KEO 2KO7 2L2S 3UF8 3UQA 3UQB 3VAW 4DZ2 4DZ3 4FN2 4G50 4GGQ
• Descriptor: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, 3-(pyridin-3-yl)propyl (2S)-1-[(3-nitrophenyl)sulfonyl]piperidine-2-carboxylate, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: ssgcid, isomerase, structural genomics, seattle structural genomics center for infectious disease, protein binding
• Biological source: Saccharomyces cerevisiae; More
• Total number of polymer chains: 2
• Total formula weight: 46846.59

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-08-09, release date: 2012-09-05, Last modification date: 2024-02-28)

• Primary citation: Begley, D.W.,Fox, D.,Jenner, D.,Juli, C.,Pierce, P.G.,Abendroth, J.,Muruthi, M.,Safford, K.,Anderson, V.,Atkins, K.,Barnes, S.R.,Moen, S.O.,Raymond, A.C.,Stacy, R.,Myler, P.J.,Staker, B.L.,Harmer, N.J.,Norville, I.H.,Holzgrabe, U.,Sarkar-Tyson, M.,Edwards, T.E.,Lorimer, D.D.; A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.; Antimicrob.Agents Chemother., 58:1458-1467, 2014; PubMed: 24366729; DOI: 10.1128/AAC.01875-13

Experimental method

X-RAY DIFFRACTION (2.45 Å)