4V9C

Allosteric control of the ribosome by small-molecule antibiotics

This is a non-PDB format compatible entry.

Summary for 4V9C

• Entry DOI: 10.2210/pdb4v9c/pdb
• Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (59 entities in total)
• Functional Keywords: nucleic acid conformation, protein biosynthesis, antibiotic, neomycin, aminoglycoside, rrf, recycling, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Escherichia coli; More
• Cellular location: Cytoplasm:
• Total number of polymer chains: 109
• Total formula weight: 4402452.12

Authors

Cate, J.H.D.,Pulk, A.,Blanchard, S.C.,Wang, L.,Feldman, M.B.,Wasserman, M.R.,Altman, R. (deposition date: 2012-07-25, release date: 2014-07-09, Last modification date: 2014-12-10)

• Primary citation: Wang, L.,Pulk, A.,Wasserman, M.R.,Feldman, M.B.,Altman, R.B.,Doudna Cate, J.H.,Blanchard, S.C.; Allosteric control of the ribosome by small-molecule antibiotics.; Nat.Struct.Mol.Biol., 19:957-963, 2012; PubMed: 22902368; DOI: 10.1038/nsmb.2360

Experimental method

X-RAY DIFFRACTION (3.3 Å)