4G37
Structure of cross-linked firefly luciferase in second catalytic conformation
Summary for 4G37
Entry DOI | 10.2210/pdb4g37/pdb |
Related | 1LCI 2D1S 3IEP 4G36 |
Descriptor | Luciferin 4-monooxygenase, 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, 4,4'-(ethylenediimino)bis[4-oxobutyrate], ... (6 entities in total) |
Functional Keywords | anl superfamily, ligase, adenylating enzymes, luciferase, domain alternation, trapped conformation, chemical cross-linker |
Biological source | Photinus pyralis (North American firefly) |
Cellular location | Peroxisome: P08659 |
Total number of polymer chains | 2 |
Total formula weight | 124213.73 |
Authors | Sundlov, J.A.,Branchini, B.R.,Gulick, A.M. (deposition date: 2012-07-13, release date: 2012-08-15, Last modification date: 2023-09-13) |
Primary citation | Sundlov, J.A.,Fontaine, D.M.,Southworth, T.L.,Branchini, B.R.,Gulick, A.M. Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism. Biochemistry, 51:6493-6495, 2012 Cited by PubMed: 22852753DOI: 10.1021/bi300934s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.396 Å) |
Structure validation
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