1LCI

FIREFLY LUCIFERASE

Summary for 1LCI

Entry DOI	10.2210/pdb1lci/pdb
Descriptor	LUCIFERASE (2 entities in total)
Functional Keywords	oxidoreductase, monooxygenase, photoprotein, luminescence
Biological source	Photinus pyralis (common eastern firefly)
Cellular location	Peroxisome: P08659
Total number of polymer chains	1
Total formula weight	60818.95
Authors	Conti, E.,Franks, N.P.,Brick, P. (deposition date: 1996-06-01, release date: 1997-03-26, Last modification date: 2024-02-14)
Primary citation	Conti, E.,Franks, N.P.,Brick, P. Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure, 4:287-298, 1996 Cited by PubMed Abstract: Firefly luciferase is a 62 kDa protein that catalyzes the production of light. In the presence of MgATP and molecular oxygen, the enzyme oxidizes its substrate, firefly luciferin, emitting yellow-green light. The reaction proceeds through activation of the substrate to form an adenylate intermediate. Firefly luciferase shows extensive sequence homology with a number of enzymes that utilize ATP in adenylation reactions. PubMed: 8805533 DOI: 10.1016/S0969-2126(96)00033-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation