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1LCI

FIREFLY LUCIFERASE

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005524molecular_functionATP binding
A0005777cellular_componentperoxisome
A0008218biological_processbioluminescence
A0016405molecular_functionCoA-ligase activity
A0046872molecular_functionmetal ion binding
A0047077molecular_functionPhotinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
A0051087molecular_functionprotein-folding chaperone binding
Functional Information from PROSITE/UniProt
site_idPS00455
Number of Residues12
DetailsAMP_BINDING Putative AMP-binding domain signature. IMNSSGSTGlPK
ChainResidueDetails
AILE195-LYS206

Catalytic Information from CSA
site_idCSA1
Number of Residues4
Detailsa catalytic site defined by CSA, PubMed 12530517
ChainResidueDetails
AHIS245
AARG218
ALYS529
ATHR343

site_idMCSA1
Number of Residues5
DetailsM-CSA 128
ChainResidueDetails
AARG218electrostatic stabiliser
AHIS245electrostatic stabiliser
ATHR343electrostatic stabiliser, hydrogen bond donor
ALYS443electrostatic stabiliser, hydrogen bond donor
ALYS529electrostatic stabiliser, hydrogen bond donor

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PDB entries from 2024-12-18

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