4FMQ

Crystal structure of human ERK2 complexed with a MAPK docking peptide

Summary for 4FMQ

Entry DOI	10.2210/pdb4fmq/pdb
Related	2XRW 2Y8O 2Y9Q 3TEI
Descriptor	Mitogen-activated protein kinase 1, MAPK DOCKING PEPTIDE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	transferase, signaling, protein-protein interaction, transferase-signaling protein complex, transferase/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P28482
Total number of polymer chains	2
Total formula weight	43914.08
Authors	Gogl, G.,Toeroe, I.,Remenyi, A. (deposition date: 2012-06-18, release date: 2012-10-31, Last modification date: 2023-09-13)
Primary citation	Garai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A. Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove. Sci.Signal., 5:ra74-ra74, 2012 Cited by PubMed: 23047924 DOI: 10.1126/scisignal.2003004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.098 Å)

Structure validation