4F8H
X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel
Summary for 4F8H
Entry DOI | 10.2210/pdb4f8h/pdb |
Descriptor | Proton-gated ion channel, (R)-ketamine, tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, ... (5 entities in total) |
Functional Keywords | ketamine, pentameric ligand-gated ion channel, ion channel, anesthetics, transport protein |
Biological source | Gloeobacter violaceus |
Total number of polymer chains | 5 |
Total formula weight | 193710.70 |
Authors | Pan, J.J.,Chen, Q.,Willenbring, D.,Kong, X.P.,Cohen, A.,Xu, Y.,Tang, P. (deposition date: 2012-05-17, release date: 2012-08-29, Last modification date: 2023-09-13) |
Primary citation | Pan, J.,Chen, Q.,Willenbring, D.,Mowrey, D.,Kong, X.P.,Cohen, A.,Divito, C.B.,Xu, Y.,Tang, P. Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine. Structure, 20:1463-1469, 2012 Cited by PubMed: 22958642DOI: 10.1016/j.str.2012.08.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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