4F8H
X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Proton-gated ion channel | polymer | 317 | 36277.7 | 5 | UniProt (Q7NDN8) Pfam (PF02931) | Gloeobacter violaceus | GLIC, Ligand-gated ion channel, LGIC |
| 2 | F, J, N, S, W (A, B, C, D, E) | (R)-ketamine | non-polymer | 237.7 | 5 | Chemie (RKE) PubChem (182137) PubChem (644025) PubChem (3821) | |||
| 3 | G, K, O, R, T... (A, B, C, D, E) | tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside | non-polymer | 538.7 | 6 | Chemie (LMD) PubChem (66678653) PubChem (4279829) PubChem (101587920) PubChem (126731035) PubChem (126735913) PubChem (101587921) PubChem (102219027) PubChem (9937070) PubChem (126735905) | |||
| 4 | H, I, L, M, P... (A, B, C, D, E) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 10 | Chemie (PC1) PubChem (65146) PubChem (94190) PubChem (10417837) | |||
| 5 | AA, BA, CA, DA, EA (A, B, C, D, E) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181388.6 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 12322.1 | |
| All* | Total formula weight | 193710.7 |
