4F7G
Crystal structure of talin autoinhibition complex
Summary for 4F7G
Entry DOI | 10.2210/pdb4f7g/pdb |
Descriptor | Talin-1 (3 entities in total) |
Functional Keywords | alpha-helix bundle, integrin activation, cell adhesion |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P26039 P26039 |
Total number of polymer chains | 2 |
Total formula weight | 48472.89 |
Authors | |
Primary citation | Song, X.,Yang, J.,Hirbawi, J.,Ye, S.,Perera, H.D.,Goksoy, E.,Dwivedi, P.,Plow, E.F.,Zhang, R.,Qin, J. A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion. Cell Res., 22:1533-1545, 2012 Cited by PubMed: 22710802DOI: 10.1038/cr.2012.97 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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