4F7G

Crystal structure of talin autoinhibition complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Talin-1	polymer	222	25613.4	1	UniProt (P26039) Pfam (PF00373) Pfam (PF02174)	Mus musculus (mouse)
2	B (B)	Talin-1	polymer	216	22859.5	1	UniProt (P26039) Pfam (PF21865)	Mus musculus (mouse)
3	C, D (A, B)	water	water		18.0	109	Chemie (HOH)

Sequence modifications

A: 206 - 405 (UniProt: P26039)

PDB	External Database	Details
Met 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
Ser 191	-	expression tag
Ser 192	-	expression tag
Gly 193	-	expression tag
Val 194	-	expression tag
Asp 195	-	expression tag
Leu 196	-	expression tag
Gly 197	-	expression tag
Thr 198	-	expression tag
Glu 199	-	expression tag
Asn 200	-	expression tag
Leu 201	-	expression tag
Tyr 202	-	expression tag
Phe 203	-	expression tag
Gln 204	-	expression tag
Ser 205	-	expression tag

B: 1654 - 1847 (UniProt: P26039)

PDB	External Database	Details
Met 1632	-	expression tag
His 1633	-	expression tag
His 1634	-	expression tag
His 1635	-	expression tag
His 1636	-	expression tag
His 1637	-	expression tag
His 1638	-	expression tag
Ser 1639	-	expression tag
Ser 1640	-	expression tag
Gly 1641	-	expression tag
Val 1642	-	expression tag
Asp 1643	-	expression tag
Leu 1644	-	expression tag
Gly 1645	-	expression tag
Thr 1646	-	expression tag
Glu 1647	-	expression tag
Asn 1648	-	expression tag
Leu 1649	-	expression tag
Tyr 1650	-	expression tag
Phe 1651	-	expression tag
Gln 1652	-	expression tag
Ser 1653	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48472.9
All*	Total formula weight	48472.9

*Water molecules are not included.