4F1L
Human Artd8 (Parp14, Bal2) - catalytic domain in complex with inhibitor A16(Z)
Summary for 4F1L
Entry DOI | 10.2210/pdb4f1l/pdb |
Related | 3GOY 3SE2 3SMI 3SMJ 4F1Q |
Descriptor | Poly [ADP-ribose] polymerase 14, (2Z)-4-[(3-carbamoylphenyl)amino]-4-oxobut-2-enoic acid, NITRATE ION, ... (4 entities in total) |
Functional Keywords | nad, adp-ribose, parp14, bal2, artd8, artd transferase domain, adp-ribosylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q460N5 |
Total number of polymer chains | 4 |
Total formula weight | 89535.20 |
Authors | Karlberg, T.,Andersson, C.D.,Lindgren, A.,Spjut, S.,Thorsell, A.G.,Ekblad, T.,Weigelt, J.,Elofsson, M.,Linusson, A.,Schuler, H. (deposition date: 2012-05-07, release date: 2012-09-05, Last modification date: 2023-09-13) |
Primary citation | Andersson, C.D.,Karlberg, T.,Ekblad, T.,Lindgren, A.E.,Thorsell, A.G.,Spjut, S.,Uciechowska, U.,Niemiec, M.S.,Wittung-Stafshede, P.,Weigelt, J.,Elofsson, M.,Schuler, H.,Linusson, A. Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening. J.Med.Chem., 55:7706-7718, 2012 Cited by PubMed: 22823910DOI: 10.1021/jm300746d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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